LAUSR

Key Points Question In congregant settings with the introduction of coronavirus disease 2019 (COVID-19), what clinical and laboratory findings are associated with an outbreak? Findings In this cohort study of 10 613 US Air Force basic trainees living congregantly in 263 cohorts, 3% were diagnosed with COVID-19 infection. Cohorts with trainees with more symptoms and lower cycle threshold values on reverse transcription–polymerase chain reaction assay were significantly associated with greater risk of transmission of COVID-19 within their cohorts. Meaning In this study, a higher number of symptoms and lower cycle threshold values were associated with subsequent clusters of outbreaks within cohorts and may be useful as risk factor measures if validated in future studies.