LAUSR

Key Points Question Do patients who receive biologic infusions at home have more adverse events requiring escalation of care compared with patients who receive biologic infusions at a facility? Findings In this cohort study of 57 220 patients with immune-mediated disease who received 752 150 biologic infusions, home infusions were associated with 25% increased odds of emergency department or hospital admission on the same or next day after infusion compared with facility infusions and 28% increased odds of permanent discontinuation of the biologic after emergency department or hospital admission. Meaning These findings suggest that the safety implications of administering biologic infusions at home need to be assessed further.