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Key Points Question What is the association of COVID-19 vaccine efficacy and coverage scenarios with and without nonpharmaceutical interventions (NPIs) with SARS-CoV-2 infections, hospitalizations, and deaths? Findings A decision analytical… Click to show full abstract
Key Points Question What is the association of COVID-19 vaccine efficacy and coverage scenarios with and without nonpharmaceutical interventions (NPIs) with SARS-CoV-2 infections, hospitalizations, and deaths? Findings A decision analytical model of North Carolina found that removing NPIs while vaccines were distributed resulted in substantial increases in infections, hospitalizations, and deaths. Furthermore, as NPIs were removed, higher vaccination coverage with less efficacious vaccines contributed to a larger reduction in risk of infection compared with more efficacious vaccines at lower coverage. Meaning These findings highlight the need for high COVID-19 vaccine coverage and continued adherence to NPIs before safely resuming many prepandemic activities.
Journal Title: JAMA Network Open
Year Published: 2021
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