LAUSR

Key Points Question How has the use of radical prostatectomy (RP) changed over time with respect to tumor risk and life expectancy (LE)? Findings In this cohort study of 5736 men treated with RP at 8 Veterans Affairs hospitals from 2000 to 2017, the proportion of low-risk tumors decreased 44%, the proportion of intermediate-risk tumors increased 29% (with favorable intermediate-risk tumors decreasing 20% and unfavorable intermediate-risk tumors increasing 11%), and the proportion of high-risk tumors increased 15%. During this period, the proportion of men treated with RP with LE less than 10 years increased 9%. Meaning These findings suggest that although use of RP has shifted away from low-risk and favorable intermediate-risk to higher-risk prostate cancer, its use among men with limited LE appears unchanged across tumor risk subgroups and increased overall.