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Progression and Regression of Chronic Kidney Disease by Age Among Adults in a Population-Based Cohort in Alberta, Canada

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Key Points Question How likely is regression of mild to severe chronic kidney disease (CKD) in adults? Findings In this population-based cohort study of adults with incident CKD, the 5-year… Click to show full abstract

Key Points Question How likely is regression of mild to severe chronic kidney disease (CKD) in adults? Findings In this population-based cohort study of adults with incident CKD, the 5-year probability of regression was similar to that of progression or kidney failure in mild (14.3% vs 14.6%), moderate (18.9% vs 16.5%), and severe (19.3% vs 20.4%) CKD. As the risk of death increased with advancing age, the risk of progression decreased substantially, whereas the probabilities of regression varied to a lesser extent and exceeded the risk of progression in moderate or severe CKD. Meaning These findings suggest that CKD regression should be considered in the allocation of health resources and in patient counseling.

Keywords: regression; chronic kidney; ckd; progression; kidney disease

Journal Title: JAMA Network Open
Year Published: 2021

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