LAUSR

Key Points Question Is cumulative social risk (ie, co-occurring sociodemographic barriers) associated with lower receipt of chemotherapy among patients with advanced colorectal cancer, and does social support moderate this association? Findings Data from a cross-sectional survey of 1087 diverse adults with stage III colorectal cancer indicated that participants with 3 or more social risk factors were less likely to receive chemotherapy than participants with 0 risk factors. The association of cumulative social risk with chemotherapy receipt was moderated by access to social support. Meaning These findings suggest that assessing cumulative social risk may identify patients with advanced colorectal cancer who are at higher risk for omitting chemotherapy.