LAUSR

Key Points Question How complex are the medication regimens for children with neurological impairment? Findings In this cross-sectional study of 123 children with neurological impairment, empirically measured Medication Regimen Complexity Index scores were high; patients were prescribed a median of 31 total daily doses of medication, 7 different dose frequencies, 6 unique dosage forms, and 5 specialized instructions. Higher Medication Regimen Complexity Index scores were associated with increased subsequent acute health care utilization. Meaning These findings suggest that clinical interventions to manage medication regimen complexity could target various aspects of these regimens, such as the simplification of dosing schedules.