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Immunogenicity Rates After SARS-CoV-2 Vaccination in People With End-stage Kidney Disease

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Key Points Question What are the immunogenicity rates in people with end-stage kidney disease receiving SARS-CoV-2 vaccines? Findings This systematic review and meta-analysis of 32 studies found that patients receiving… Click to show full abstract

Key Points Question What are the immunogenicity rates in people with end-stage kidney disease receiving SARS-CoV-2 vaccines? Findings This systematic review and meta-analysis of 32 studies found that patients receiving dialysis had lower immunogenicity rates after first and second vaccine doses than those not receiving dialysis. Prevalence of diabetes had an inverse linear association with immunogenicity rate. Meaning These findings suggest that the immunogenicity rate after vaccination was lower in patients receiving dialysis and that diabetes might be a risk factor for nonresponse to vaccination.

Keywords: stage kidney; immunogenicity; immunogenicity rates; vaccination; end stage; people end

Journal Title: JAMA Network Open
Year Published: 2021

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