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Epidemiology and Costs of Postsepsis Morbidity, Nursing Care Dependency, and Mortality in Germany, 2013 to 2017

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Key Points Question How common are new and co-occurring medical, cognitive, or psychological diagnoses, new nursing care dependency, and postacute mortality among individuals who survive sepsis? Findings In this cohort… Click to show full abstract

Key Points Question How common are new and co-occurring medical, cognitive, or psychological diagnoses, new nursing care dependency, and postacute mortality among individuals who survive sepsis? Findings In this cohort study of 116 507 survivors of hospital-treated sepsis in Germany, nearly three-quarters had new medical, cognitive, or psychological diagnoses; nearly one-third were newly dependent on nursing care; and more than of 3 in 10 died in first year post sepsis. New diagnoses co-occurred in one-quarter of participants and affected sepsis survivors irrespective of preexisting diagnoses, sepsis severity, and intensive care unit treatment. Meaning These findings suggest that postsepsis morbidity may be more common and severe than previously believed, calling for increased efforts to prevent and treat the sequelae of severe infections.

Keywords: sepsis; care dependency; epidemiology; care; nursing care

Journal Title: JAMA Network Open
Year Published: 2021

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