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Key Points Question Can the accuracy of prognosis prediction be improved using a tumor-associated collagen signature of gastric cancer (TACSGC) to detect patients who are likely to benefit from adjuvant… Click to show full abstract
Key Points Question Can the accuracy of prognosis prediction be improved using a tumor-associated collagen signature of gastric cancer (TACSGC) to detect patients who are likely to benefit from adjuvant chemotherapy for GC? Findings In this cohort study of 519 patients, a low TACSGC level was associated with a better prognosis, and patients with stage II and III GC with a low TACSGC level were more likely to benefit from adjuvant chemotherapy. Meaning The findings suggest that TACSGC may improve the accuracy of prognosis prediction and provide a helpful reference for decision-making regarding adjuvant chemotherapy in GC.
Journal Title: JAMA Network Open
Year Published: 2021
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