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Incidence and Outcomes Associated With Clostridioides difficile Infection in Solid Organ Transplant Recipients

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Key Points Question What are the incidence and outcomes associated with posttransplant Clostridioides difficile infection (CDI) in people who have undergone solid organ transplant? Findings In this cohort study including… Click to show full abstract

Key Points Question What are the incidence and outcomes associated with posttransplant Clostridioides difficile infection (CDI) in people who have undergone solid organ transplant? Findings In this cohort study including 10 724 patients, posttransplant CDI was associated with a 90-day mortality incidence of 17%. Late-onset CDI was associated with a greater risk of short- and long-term mortality compared with early-onset CDI. Meaning The findings of this large cohort of organ transplant recipients suggest a trend toward increasing risk of CDI over time.

Keywords: outcomes associated; organ transplant; clostridioides difficile; incidence outcomes; incidence; difficile infection

Journal Title: JAMA Network Open
Year Published: 2021

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