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Association of Arterial Hyperoxia With Outcomes in Critically Ill Children

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Key Points Question What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? Findings This systematic review of 16 studies… Click to show full abstract

Key Points Question What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? Findings This systematic review of 16 studies and meta-analysis of 11 studies comprising a total of 23 204 patients found an association between hyperoxia and mortality in children admitted to the pediatric intensive care unit. Meaning These findings suggest that hyperoxia is associated with harm in critically ill children; the clinical implication of this association needs to be addressed in future studies.

Keywords: critically ill; ill children; association arterial; hyperoxia outcomes; arterial hyperoxia

Journal Title: JAMA Network Open
Year Published: 2022

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