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Optimal Sequencing of Deceased Donor and Live Donor Kidney Transplant Among Pediatric Patients With Kidney Failure

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Key Points Question If a pediatric recipient has a live donor (LD) kidney option available, should they opt for this transplant first or opt for a deceased donor (DD) transplant… Click to show full abstract

Key Points Question If a pediatric recipient has a live donor (LD) kidney option available, should they opt for this transplant first or opt for a deceased donor (DD) transplant first and save the LD option for later if required? Findings In this decision analytical model, opting for an LD transplant first most often provides more remaining life-years. However, opting for a DD transplant first and saving an LD for retransplant after the DD transplant fails may result in a similar number of remaining life-years for recipients aged 10 to 14 years while the LD remains available. Meaning With the contemporary trend of proportionately fewer LD kidney transplants for pediatric recipients, programs should promote LD kidney transplant as the first option for pediatric recipients.

Keywords: live donor; kidney; donor kidney; transplant first; transplant

Journal Title: JAMA Network Open
Year Published: 2022

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