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Key Points Question Can loop-mediated isothermal amplification (LAMP)-based methodology coupled with smartphone detection provide an inexpensive, rapid, sensitive, and reliable platform for COVID-19 and influenza testing? Findings In this cohort… Click to show full abstract
Key Points Question Can loop-mediated isothermal amplification (LAMP)-based methodology coupled with smartphone detection provide an inexpensive, rapid, sensitive, and reliable platform for COVID-19 and influenza testing? Findings In this cohort study of saliva samples from 50 community-based patients, the smartphone-based LAMP assay detected SARS-CoV-2 infection and exhibited concordance with reverse transcriptase–quantitative polymerase chain reaction tests. Meaning These findings suggest that the smartphone-based LAMP assay offers an additional tool to detect COVID-19 that can be readily modified in response to novel SARS-CoV-2 variants and other pathogens with pandemic potential including influenza.
Journal Title: JAMA Network Open
Year Published: 2022
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