LAUSR

Key Points Question What are the risk factors, causes, timing, and circumstances of death for infants born at 24 0/7 to 27 6/7 weeks of gestation? Findings In this cohort study of 941 infants enrolled in the Preterm Erythropoietin Neuroprotection Trial, mortality was lower and infants lived longer than in previous decades, and the most common cause of death was respiratory distress or failure. Survival increased with postnatal day and postmenstrual age; half of the dying infants received comfort care. Meaning The findings of this study suggest that prognostication for extremely preterm infants should consider both gestational and postnatal age.