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Model-Estimated Association Between Simulated US Elementary School–Related SARS-CoV-2 Transmission, Mitigation Interventions, and Vaccine Coverage Across Local Incidence Levels

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Key Points Question How is COVID-19 incidence in elementary school communities associated with in-school mitigation (eg, masks), vaccination, and local incidence, and when should decision-makers add or remove mitigation measures?… Click to show full abstract

Key Points Question How is COVID-19 incidence in elementary school communities associated with in-school mitigation (eg, masks), vaccination, and local incidence, and when should decision-makers add or remove mitigation measures? Findings In this decision analytic model with a simulated population of 638 students and 60 educators and staff in an elementary school, school community incidence decreased with mitigation and vaccination and increased with local incidence. Thresholds for changing mitigation measures depended on the objective (eg, minimizing likelihood of any in-school transmission vs maintaining cases within acceptable limits). Meaning These findings suggest that appropriate increases and decreases for in-school mitigation depend on policy makers’ goals; responsive plans, in which mitigation is deployed based on local COVID-19 incidence and vaccine uptake, may be appropriate.

Keywords: elementary school; incidence; transmission; local incidence; school; mitigation

Journal Title: JAMA Network Open
Year Published: 2022

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