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Association of Preeclampsia With Incident Stroke in Later Life Among Women in the Framingham Heart Study

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Key Points Question Is preeclampsia associated with later-life stroke among women after accounting for time-varying covariates? Findings In this cohort study of 1435 women with and without a history of… Click to show full abstract

Key Points Question Is preeclampsia associated with later-life stroke among women after accounting for time-varying covariates? Findings In this cohort study of 1435 women with and without a history of preeclampsia who participated in the Framingham Heart Study, after adjustment for age and time-varying vascular risk factors, women with a history of preeclampsia had a more than 3-fold higher risk of experiencing a stroke in later life compared with women who did not have a history of preeclampsia. Meaning The findings suggest that preeclampsia may be an independent risk factor for later-life stroke among women after controlling for vascular risk factors across the life course.

Keywords: framingham heart; study; among women; preeclampsia; later life; life

Journal Title: JAMA Network Open
Year Published: 2021

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