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Key Points Question What is the association between ondansetron exposure during pregnancy and the risk of adverse fetal outcomes? Findings In this meta-analysis of cohort studies of 456 963 pregnancies in… Click to show full abstract
Key Points Question What is the association between ondansetron exposure during pregnancy and the risk of adverse fetal outcomes? Findings In this meta-analysis of cohort studies of 456 963 pregnancies in 3 countries, treatment with ondansetron was not significantly associated with increased risk of fetal death, spontaneous abortion, stillbirth, or major congenital malformations compared with other antiemetics. Meaning These findings suggest that ondansetron use during pregnancy is not associated with an increased risk of adverse fetal outcomes compared with the use of other antiemetics.
Journal Title: JAMA Network Open
Year Published: 2021
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