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Effect of Clinical Decision Support on Cardiovascular Risk Among Adults With Bipolar Disorder, Schizoaffective Disorder, or Schizophrenia

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Key Points Question Does a clinical decision support system aimed at primary care clinicians improve cardiovascular health for people with serious mental illness? Findings In this cluster randomized clinical trial… Click to show full abstract

Key Points Question Does a clinical decision support system aimed at primary care clinicians improve cardiovascular health for people with serious mental illness? Findings In this cluster randomized clinical trial of 8937 patients with serious mental illness, intervention patients’ rate of change in total modifiable cardiovascular risk over 12 months was 4% lower than control patients’ rate of change. There were no significant differences in individual modifiable risk factors. Meaning Although treatment effects favored the intervention, the results were driven by cumulative effects of incremental and mostly nonsignificant changes in individual modifiable cardiovascular risk factors.

Keywords: clinical decision; decision support; risk; cardiovascular risk; disorder

Journal Title: JAMA Network Open
Year Published: 2022

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