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Sustaining Antimicrobial Stewardship in a High–Antibiotic Resistance Setting

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Key Points Question Can the outcomes associated with an antimicrobial stewardship program be sustained in the long term? Findings In this cohort study, after implementation of prospective review and feedback,… Click to show full abstract

Key Points Question Can the outcomes associated with an antimicrobial stewardship program be sustained in the long term? Findings In this cohort study, after implementation of prospective review and feedback, the use trends increased for piperacillin-tazobactam and carbapenems and declined for other broad-spectrum antibiotics. After the addition of a computerized decision support system, the use trends decreased for piperacillin-tazobactam and carbapenems and for other broad-spectrum antibiotics. Meaning These findings suggest that concurrent use of prospective review and feedback and a computerized decision support system may help to sustain the outcomes associated with antimicrobial stewardship programs.

Keywords: stewardship; antibiotic resistance; stewardship high; antimicrobial stewardship; sustaining antimicrobial; high antibiotic

Journal Title: JAMA Network Open
Year Published: 2022

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