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Key Points Question How does the percentage of patients who withdraw from adjuvant trials because of adverse events compare with patients who withdraw from metastatic trials for the same drug?… Click to show full abstract
Key Points Question How does the percentage of patients who withdraw from adjuvant trials because of adverse events compare with patients who withdraw from metastatic trials for the same drug? Findings In this cross-sectional study, the adjuvant setting was associated with higher rates of discontinuation of drugs because of adverse events or patient withdrawal than in the metastatic setting. Meaning These results suggest that adverse effects of treatments in the adjuvant setting must be considered when planning a patient’s course of treatment and reaching the therapeutic window.
Journal Title: JAMA Network Open
Year Published: 2022
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