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Association Between Dexamethasone Treatment After Hospital Discharge for Patients With COVID-19 Infection and Rates of Hospital Readmission and Mortality

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Key Points Question Is continuing use of dexamethasone, 6 mg/d, at discharge for patients with COVID-19 who received less than 10 days of dexamethasone treatment during hospitalization associated with readmission… Click to show full abstract

Key Points Question Is continuing use of dexamethasone, 6 mg/d, at discharge for patients with COVID-19 who received less than 10 days of dexamethasone treatment during hospitalization associated with readmission or mortality after discharge? Findings In a cohort of 1164 patients with COVID-19 who received less than 10 days of dexamethasone, 6 mg/d, during hospitalization, the rate of readmission or mortality within 14 days of discharge was 9.1% among patients who continued dexamethasone treatment compared with 11.4% among patients who did not. The difference was not statistically significant. Meaning The findings of this study suggest that prescribing dexamethasone at discharge for patients hospitalized with COVID-19 who received less than 10 days of dexamethasone is not associated with a reduction in readmission or mortality.

Keywords: discharge patients; readmission mortality; discharge; patients covid

Journal Title: JAMA Network Open
Year Published: 2022

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