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Key Points Question What are the risks of venous thromboembolism (VTE) after lower extremity revascularization (LER) for peripheral artery disease (PAD), and is use of low-dose rivaroxaban plus aspirin associated… Click to show full abstract
Key Points Question What are the risks of venous thromboembolism (VTE) after lower extremity revascularization (LER) for peripheral artery disease (PAD), and is use of low-dose rivaroxaban plus aspirin associated with risk of VTE after LER? Findings In this cohort study of 6564 patients undergoing LER for PAD, the 3-year rate of VTE in patients receiving placebo was 1.66%, and low-dose rivaroxaban plus aspirin was associated with reduced risk for VTE. Meaning These findings suggest that patients who underwent LER for PAD were at risk for VTE in addition to arterial thrombotic events, and low-dose rivaroxaban plus aspirin should be considered for reduction of the full spectrum of thrombotic risk.
Journal Title: JAMA Network Open
Year Published: 2022
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