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Neurobehavior in the Neonatal Intensive Care Unit-Window to the Future?

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556 infants born at less than 30 weeks’ gestation at 9 NICUs in the United States were evaluated with the NNNS prior to hospital discharge and then assessed at 2… Click to show full abstract

556 infants born at less than 30 weeks’ gestation at 9 NICUs in the United States were evaluated with the NNNS prior to hospital discharge and then assessed at 2 years’ corrected age with the Bayley Scales of Infant and Toddler Development, third edition (Bayley-III), and the Child Behavior Checklist (CBCL). Infants were classified as high medical risk if they had at least 2 medical morbidities. Infants were classified as high behavioral risk if they had either of 2 (of 6) nonoptimal cohort-specific profiles on the NNNS. The key finding of this study was that high medical and high behavioral risk in the NICU were 4 times more likely to have 85 at 2 years’ corrected age than infants with low behavioral and low medical risk. the of CBCL internalizing and total problem in the clinical range was twice as in the group of high behavioral the group behavioral on the NNNS. Adjusted for behavioral problems was significantly elevated in the high behavioral risk and low medical risk group compared with the low behavioral and low medical risk group.

Keywords: high behavioral; behavioral risk; group; low medical; risk; medical risk

Journal Title: JAMA network open
Year Published: 2022

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