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Conducted in that fourth doses of the Pfizer-BioNTech vaccine to all adults aged 60 years or older January 2022, this observational study compared immune response—measured as anti–spike protein immunoglobulin G… Click to show full abstract
Conducted in that fourth doses of the Pfizer-BioNTech vaccine to all adults aged 60 years or older January 2022, this observational study compared immune response—measured as anti–spike protein immunoglobulin G (IgG) antibody titers—before and after third and fourth vaccine doses, thereby providing information on the magnitude and duration of the immune boost. The results show a significant but transient increase in IgG titers after the third dose, decreasing approximately 10-fold after 5 months; titers were then restored immediately after a fourth
Journal Title: JAMA network open
Year Published: 2022
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