Key Points Question How effective is vaccination against COVID-19 after recovery from prior SARS-CoV-2 infection? Findings In this cohort study of more than 95 000 Rhode Island residents from March 2020… Click to show full abstract
Key Points Question How effective is vaccination against COVID-19 after recovery from prior SARS-CoV-2 infection? Findings In this cohort study of more than 95 000 Rhode Island residents from March 2020 to December 2021, including residents and employees of long-term congregate care (LTCC) facilities, completion of the primary vaccination series after recovery from COVID-19 was associated with 49% protection from reinfection among LTCC residents, 47% protection among LTCC employees, and 62% protection in the general population during periods when wild type, Alpha, and Delta strains of SARS-CoV-2 were predominant. Meaning These findings suggest that among people who have recovered from COVID-19, subsequent completion of the primary vaccination series reduced the risk of reinfection by approximately half.
               
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