LAUSR

Key Points Question Can peer-led behavioral interventions in the emergency department for patients who have had a recent opioid overdose increase short-term treatment engagement after the emergency department visit? Findings In this randomized clinical trial of 648 emergency department patients at high risk of opioid overdose, there was no difference in treatment engagement within 30 days of the visit for participants who received a peer-led intervention vs those who received a standard behavioral intervention by a clinical social worker (32% vs 30%). Meaning An emergency department–based behavioral intervention is likely effective in promoting treatment engagement, but who delivers the intervention may be less influential on short-term outcomes.