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Overall Survival Benefits of Cancer Drugs Approved in China From 2005 to 2020

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Key Points Question What is the overall survival benefit of cancer drugs approved in China between 2005 and 2020? Findings In this mixed-methods study comprising a systematic review and cross-sectional… Click to show full abstract

Key Points Question What is the overall survival benefit of cancer drugs approved in China between 2005 and 2020? Findings In this mixed-methods study comprising a systematic review and cross-sectional analysis of 78 cancer drugs for 141 indications, 68 new cancer drug indications approved by Chinese authorities between 2005 and 2020 had documented evidence of overall survival benefit, and 34 did not prolong life. Meaning Given regulatory reforms in recent years, these findings highlight the need to routinely monitor the clinical benefits of new cancer therapies in China.

Keywords: cancer; cancer drugs; drugs approved; approved china; overall survival; 2005 2020

Journal Title: JAMA Network Open
Year Published: 2022

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