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Utility of Newborn Dried Blood Spots to Ascertain Seroprevalence of SARS-CoV-2 Antibodies Among Individuals Giving Birth in New York State, November 2019 to November 2021

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Key Points Question Can analysis of newborn dried blood spot (DBS) samples be used to monitor SARS-CoV-2 seroprevalence in infants and individuals giving birth? Findings In this repeated cross-sectional study,… Click to show full abstract

Key Points Question Can analysis of newborn dried blood spot (DBS) samples be used to monitor SARS-CoV-2 seroprevalence in infants and individuals giving birth? Findings In this repeated cross-sectional study, DBS samples from 415 293 infants born in New York State from November 1, 2019, to November 30, 2021, were analyzed for SARS-CoV-2 antibodies. Statewide and regional seroprevalence data reflect the fluctuations in reported COVID-19 cases and vaccinations among reproductive-aged females during this period in New York State. Meaning These findings suggest that antibody testing of newborn DBS samples is an effective way to conduct large-scale monitoring of SARS-CoV-2 seroprevalence among individuals recently giving birth.

Keywords: york state; seroprevalence; new york; giving birth; sars cov

Journal Title: JAMA Network Open
Year Published: 2022

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