Key Points Question What clinical features are associated with survival in patients with brain metastasis from gastroesophageal adenocarcinoma? Findings In this cohort study of 68 patients with brain metastasis from… Click to show full abstract
Key Points Question What clinical features are associated with survival in patients with brain metastasis from gastroesophageal adenocarcinoma? Findings In this cohort study of 68 patients with brain metastasis from gastroesophageal adenocarcinoma, median survival was 8.7 months from diagnosis, with overall survival rates of 35% at 1 year and 24% at 2 years. Patients with Eastern Cooperative Oncology Group performance status of 2 or greater and who received no surgery or radiotherapy had significantly decreased survival in a multivariable analysis. Meaning These findings suggest that modern treatment approaches are associated with improved prognosis for patients with brain metastasis from gastroesophageal adenocarcinoma.
               
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