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Geographic and Racial Disparities in Access to Chimeric Antigen Receptor–T Cells and Bispecific Antibodies Trials for Multiple Myeloma

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Key Points Question Is there equitable geographic access to chimeric antigen receptor–T cells (CAR-T) and bispecific antibodies trials for multiple myeloma in the US? Findings In this cross-sectional study of… Click to show full abstract

Key Points Question Is there equitable geographic access to chimeric antigen receptor–T cells (CAR-T) and bispecific antibodies trials for multiple myeloma in the US? Findings In this cross-sectional study of data from 69 clinical trials in the US, 34% of the states analyzed had no CAR-T or bispecific clinical trial openings. There are limited open sites in states with the highest percentages of Black residents. Meaning These results suggest that the current distribution of CAR-T and bispecific antibodies trials for multiple myeloma does not allow for equitable access for Black patients.

Keywords: trials multiple; multiple myeloma; antibodies trials; access chimeric; bispecific antibodies

Journal Title: JAMA Network Open
Year Published: 2022

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