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Key Points Question What is the risk of cerebral venous thrombosis (CVT) after diagnosis of SARS-CoV-2 infection compared with after messenger RNA (mRNA)-based SARS-CoV-2 vaccination? Findings In this observational cohort… Click to show full abstract
Key Points Question What is the risk of cerebral venous thrombosis (CVT) after diagnosis of SARS-CoV-2 infection compared with after messenger RNA (mRNA)-based SARS-CoV-2 vaccination? Findings In this observational cohort study of 62 447 individuals with SARS-CoV-2 infection and 3 006 662 individuals who received mRNA-based SARS-CoV-2 vaccine in Singapore from January 23, 2020, to August 3, 2021, the incidence rate ratio of CVT requiring hospitalization within 6 weeks of SARS-CoV-2 infection was 32 times higher compared with after mRNA-based SARS-CoV-2 vaccination. Meaning These findings suggest that the risk of CVT after SARS-CoV-2 infection is higher than after mRNA-based SARS-CoV-2 vaccination.
Journal Title: JAMA Network Open
Year Published: 2022
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