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Key Points Question Is cerebral blood supply associated with cerebral tissue integrity? Findings In this cohort study of 732 healthy adults, at 5-year follow-up, significant associations between lower regional cerebral… Click to show full abstract
Key Points Question Is cerebral blood supply associated with cerebral tissue integrity? Findings In this cohort study of 732 healthy adults, at 5-year follow-up, significant associations between lower regional cerebral blood flow and decreased integrity of brain tissue were observed in critical brain regions. The association was most pronounced in white matter tissue. Meaning This finding suggests that cerebral blood flow might be an early risk factor of future change in cerebral tissue integrity among healthy adults.
Journal Title: JAMA Network Open
Year Published: 2022
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