LAUSR

Key Points Question Is a self-cut transvaginal mesh procedure vs a commercial mesh-kit procedure effective and safe for the treatment of women with symptomatic pelvic organ prolapse? Findings In this randomized clinical trial including 336 women undergoing transvaginal mesh procedures, 95.9% of women in the self-cut mesh group experienced outcomes that met the definition of composite success, which was statistically noninferior to the 87.4% surgical success rate in the mesh-kit group. The self-cut mesh procedure also reduced hospitalization costs by 40.4%. Meaning This study found that the use of self-cut mesh was effective, safe, and less expensive than a commercial mesh kit for the transvaginal surgical treatment of women with pelvic organ prolapse, suggesting that self-cut mesh procedures may be advantageous for some patients in countries with low and middle income.