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Remission and Relapse of Dyslipidemia After Vertical Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass in a Racially and Ethnically Diverse Population

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Key Points Question Do dyslipidemia outcomes up to 4 years after surgery differ between patients undergoing vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB)? Findings This comparative effectiveness study… Click to show full abstract

Key Points Question Do dyslipidemia outcomes up to 4 years after surgery differ between patients undergoing vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB)? Findings This comparative effectiveness study included 8265 racially and ethnically diverse patients who underwent VSG or RYGB and was conducted with a local instrumental variable approach to adjust for confounding in the choice of operation. Dyslipidemia remission was higher for patients who underwent RYGB (59%) than those who underwent VSG (52%) after 4 years, with high rates of relapse that were similar for RYGB and VSG during that time (21% vs 24%). Meaning These findings suggest that patients should be monitored closely throughout their postoperative course to maximize the benefits of these operations for treatment of dyslipidemia.

Keywords: roux gastric; racially ethnically; gastric bypass; sleeve gastrectomy; dyslipidemia; vertical sleeve

Journal Title: JAMA Network Open
Year Published: 2022

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