"Synergistic Associations of PNPLA3 I148M Variant, Alcohol Intake, and Obesity With Risk of Cirrhosis, Hepatocellular Carcinoma, and Mortality"

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This cohort study assesses the association of behavioral risk factors and genetic variants with risk of liver disease–related morbidity and mortality among middle-aged individuals. Click to show full abstract

This cohort study assesses the association of behavioral risk factors and genetic variants with risk of liver disease–related morbidity and mortality among middle-aged individuals.

Keywords: synergistic associations; pnpla3 i148m; mortality; risk; associations pnpla3; i148m variant

Journal Title: JAMA Network Open
Year Published: 2022

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