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Key Points Question Are lipid trajectory patterns over the life course associated with cardiovascular disease risk in midlife? Findings In this cohort study of 1201 participants with multiple lipid measurements… Click to show full abstract
Key Points Question Are lipid trajectory patterns over the life course associated with cardiovascular disease risk in midlife? Findings In this cohort study of 1201 participants with multiple lipid measurements from childhood to adulthood, discrete lifetime lipid trajectories were associated with subclinical atherosclerosis in midlife. Meaning These results suggest that the longitudinal trajectory patterns of lipid levels could be used to predict future cardiovascular risk; maintaining optimal lipid levels across the lifespan may be warranted to reduce cardiovascular risk.
Journal Title: JAMA Network Open
Year Published: 2022
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