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Survival Benefit of First Single-Organ Deceased Donor Kidney Transplantation Compared With Long-term Dialysis Across Ages in Transplant-Eligible Patients With Kidney Failure

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Key Points Question What is the difference in 10-year restricted mean survival time when receiving a kidney transplant versus remaining on the wait list and continuing dialysis for transplant-eligible patients… Click to show full abstract

Key Points Question What is the difference in 10-year restricted mean survival time when receiving a kidney transplant versus remaining on the wait list and continuing dialysis for transplant-eligible patients with kidney failure across different ages? Findings In this cohort study including 4445 adults on the wait list for their first single-organ deceased donor kidney transplant, application of target trial emulation methods showed a difference in terms of restricted mean survival times. Kidney transplant prolonged life expectancy across patient ages compared with continuing dialysis. Meaning The findings of this study suggest that transplant-eligible patients with kidney failure should not be excluded from transplant programs based on their age.

Keywords: eligible patients; dialysis; patients kidney; kidney failure; transplant eligible

Journal Title: JAMA Network Open
Year Published: 2022

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