LAUSR

Key Points Question Can criteria for potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) be used to identify inadequate drug treatment in older people? Findings In this diagnostic study, receiver operating characteristic (ROC) curves for 3 PIM/PPO criteria sets showed poor to fair performance comparable with merely counting the number of drugs. Meaning The findings of this study suggest that using these PIM/PPO criteria sets as indicators of drug treatment quality, and within core outcome sets for the evaluation of interventions aimed at improved prescribing, may not provide valid results; the tools misclassify a substantial proportion of patients, both those with inadequate and those with adequate drug treatment.