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Use of the Cancer and Aging Research Group Predictive Model for Chemotherapy-Related Toxic Effects in a Multiethnic, Older Adult Asian Population

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Key Points Question Is the Cancer and Aging Research Group (CARG) chemotherapy toxicity prediction model for older adults applicable in a multiethnic Asian population? Findings In this prognostic study, 200… Click to show full abstract

Key Points Question Is the Cancer and Aging Research Group (CARG) chemotherapy toxicity prediction model for older adults applicable in a multiethnic Asian population? Findings In this prognostic study, 200 older Asian adults underwent a geriatric assessment, and their risk of chemotherapy-related toxic effects was calculated with the CARG model. The area under the receiver operating characteristic curve for the CARG model was 0.74, indicating that the model retained good discrimination in the study population. Meaning The results of this prognostic study support the validity of the CARG prediction model in older Asian adults.

Keywords: cancer aging; asian population; research group; model; population; aging research

Journal Title: JAMA Network Open
Year Published: 2022

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