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Association of Intravenous Potassium and Magnesium Administration With Spontaneous Conversion of Atrial Fibrillation and Atrial Flutter in the Emergency Department

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Key Points Question Is the administration of potassium and magnesium associated with the probability of spontaneous conversion of nonpermanent atrial fibrillation and atrial flutter in the emergency department? Findings In… Click to show full abstract

Key Points Question Is the administration of potassium and magnesium associated with the probability of spontaneous conversion of nonpermanent atrial fibrillation and atrial flutter in the emergency department? Findings In this cohort study that included 2546 episodes of atrial fibrillation and 573 episodes of atrial flutter, administration of potassium and magnesium was associated with higher rates of spontaneous conversion in atrial fibrillation vs no administration (19.2% vs 10.4%) during patients’ stay in the emergency department. However, there was no association with atrial flutter (13.0% vs 12.5%). Meaning The findings of this study suggest that administration of potassium and magnesium might lessen the need for antiarrhythmic therapy and the potential adverse effects in patients with nonpermanent atrial fibrillation.

Keywords: atrial flutter; potassium magnesium; atrial fibrillation; administration

Journal Title: JAMA Network Open
Year Published: 2022

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