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Associations of Cardiometabolic Multimorbidity With All-Cause and Coronary Heart Disease Mortality Among Black Adults in the Jackson Heart Study

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Key Points Question Is there an association of increasing number of cardiometabolic comorbidities (diabetes, stroke, and coronary heart disease [CHD]) with all-cause mortality and CHD mortality in a population of… Click to show full abstract

Key Points Question Is there an association of increasing number of cardiometabolic comorbidities (diabetes, stroke, and coronary heart disease [CHD]) with all-cause mortality and CHD mortality in a population of US Black adults? Findings In this cohort study of 5064 Black adults followed-up for 15 years, participants with cardiometabolic morbidities individually and collectively showed statistically significant multiplicative increased risks of all-cause and CHD mortality. Meaning These findings suggest that a higher number of cardiometabolic comorbidities was associated with multiplicative increased risks of all-cause mortality and CHD mortality; thus, primordial and primary prevention of cardiometabolic morbidities are critical to reduce disparities in mortality.

Keywords: black adults; coronary heart; cause; mortality; heart; heart disease

Journal Title: JAMA Network Open
Year Published: 2022

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