LAUSR

Key Points Question Does COVID-19 vaccination prevent intensive care unit (ICU) admission for COVID-19 pneumonia and improve patient outcomes? Findings In this cohort study of more than 10 million people, vaccines based on mRNA technology or adenoviral vectors significantly decreased the risk of ICU admission for COVID-19 pneumonia. ICU and hospital mortality, adjusted for age, heart disease and Pao2/FiO2 at ICU admission, were similar between vaccinated and unvaccinated patients. Meaning COVID-19 vaccines were associated with a lower ICU admission for COVID-19 pneumonia, while no significant association was detected with ICU and hospital mortality.