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Key Points Question What is the efficacy of single wound infiltration with bupivacaine combined with adrenaline during cesarean delivery for the reduction of postoperative pain scores and opioid use? Findings… Click to show full abstract
Key Points Question What is the efficacy of single wound infiltration with bupivacaine combined with adrenaline during cesarean delivery for the reduction of postoperative pain scores and opioid use? Findings In this randomized clinical trial that included 288 women who underwent cesarean delivery at term, single wound infiltration with bupivacaine and adrenaline significantly reduced postoperative pain and postpartum use of rescue opioid analgesics. There were no intervention-related adverse effects. Meaning These findings suggest intraoperative infiltration of the wound with single administration of bupivacaine and adrenaline in women undergoing a cesarean delivery is efficacious, safe, and easy to perform.
Journal Title: JAMA Network Open
Year Published: 2022
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