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Poverty, Cortical Structure, and Psychopathologic Characteristics in Adolescence

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Key Points Question Is poverty associated with increased internalizing and externalizing problems in early adolescence, and if so, do cortical morphologic changes mediate the association? Findings In a cohort study… Click to show full abstract

Key Points Question Is poverty associated with increased internalizing and externalizing problems in early adolescence, and if so, do cortical morphologic changes mediate the association? Findings In a cohort study of 7569 early adolescents aged 9 to 10 years in the Adolescent Brain Cognitive Development Study, living below the federal poverty threshold was associated with an increase in externalizing problems during 1 year. Decreases in cortical surface area and volume of numerous brain regions partially explained this association. Meaning The findings of this study suggest a possible pathway from childhood poverty to increased externalizing problems in early adolescents through cortical morphologic changes.

Keywords: externalizing problems; poverty cortical; psychopathologic characteristics; poverty; structure psychopathologic; cortical structure

Journal Title: JAMA Network Open
Year Published: 2022

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