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Association of Smoking With Patient Characteristics and Outcomes in Small Cell Lung Carcinoma, 2011-2018

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Key Points Question Do patient characteristics of smokers and never-smokers differ among patients with small cell lung carcinoma (SCLC)? Findings In this cohort study examining 225 788 patients with lung cancer,… Click to show full abstract

Key Points Question Do patient characteristics of smokers and never-smokers differ among patients with small cell lung carcinoma (SCLC)? Findings In this cohort study examining 225 788 patients with lung cancer, among patients with SCLC, there were more older individuals, more women, more patients with a poor performance status and in an advanced stage of cancer, and more patients who did not receive treatment among never-smokers than among smokers. Never-smokers, particularly men, experienced worse outcomes. Meaning The findings of this study suggest that clinical characteristics and outcomes of patients with SCLC differ between smokers and never-smokers.

Keywords: lung carcinoma; never smokers; characteristics outcomes; patient characteristics; small cell; cell lung

Journal Title: JAMA Network Open
Year Published: 2022

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