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Analysis of Time to Diagnosis and Outcomes Among Adults With Primary Hyperparathyroidism

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Key Points Question What outcomes are associated with delays in the diagnosis and treatment of primary hyperparathyroidism (PHP)? Findings In this large database cohort study of 135 034 patients with hypercalcemia,… Click to show full abstract

Key Points Question What outcomes are associated with delays in the diagnosis and treatment of primary hyperparathyroidism (PHP)? Findings In this large database cohort study of 135 034 patients with hypercalcemia, those who were identified as high-risk and without a diagnosis and whose duration of workup or time from diagnosis to treatment exceeded 1 year experienced increased disease sequelae. Meaning These findings suggest that missed diagnoses and prolonged time to diagnosis and treatment of PHP are associated with increased disease burden.

Keywords: diagnosis treatment; diagnosis; primary hyperparathyroidism; time diagnosis

Journal Title: JAMA Network Open
Year Published: 2022

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