LAUSR

Key Points Question Do outcomes between patients with and without atrial fibrillation (AF) differ following mechanical thrombectomy (MT) for acute ischemic stroke (AIS)? Findings This systematic review and meta-analysis including 10 studies with 6543 found that patients with AF had similar rates of modified Rankin Scale scores of 0 to 2, symptomatic intracranial hemorrhage, and thrombolysis in cerebral infarction scores of 2b to 3 compared with patients without AF following MT for AIS; however, patients with AF had significantly greater rates of 90-day mortality. Patients with AF were a mean of 10.17 years older and had a greater number of comorbidities and risk factors for AIS compared with patients without AF. Meaning These findings suggest that despite similar rates of successful reperfusion, patients with AF experienced worse outcomes following MT for AIS, which may be attributed to their greater age and greater number of comorbidities.