LAUSR

Key Points Question Is the interaction between race and social determinants of health (SDOH) associated with racial disparities in prostate cancer outcomes? Findings This meta-analysis of 47 studies and 1 019 908 patients compared prostate cancer–specific mortality (PCSM) and overall survival between Black and White men. In studies with minimal accounting for SDOH, Black patients had significantly higher PCSM than White patients; however, Black men had significantly lower PCSM in studies with greater accounting for SDOH. Meaning This study suggests that the interaction between race and SDOH is significantly associated with racial disparities in health care; collecting and assessing SDOH variables in research may help to create strategies that increase health equity.