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Cost-effectiveness of Novel Macrophage-Regulating Treatment for Wound Healing in Patients With Diabetic Foot Ulcers From the Taiwan Health Care Sector Perspective

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Key Points Question Is adding a novel macrophage-regulating drug, ON101 cream, to general wound care (GWC) cost-effective compared with GWC alone for treating diabetic foot ulcers (DFUs) from a health… Click to show full abstract

Key Points Question Is adding a novel macrophage-regulating drug, ON101 cream, to general wound care (GWC) cost-effective compared with GWC alone for treating diabetic foot ulcers (DFUs) from a health care sector perspective? Findings In this economic evaluation, the ON101 with GWC strategy vs GWC alone strategy gained more wound healing events, averted more DFU-related complications, and cost $14 922/quality-adjusted life-year gained. Meaning In this study, ON101-enhanced GWC was cost-effective vs GWC alone at a willingness-to-pay threshold of $32 787/quality-adjusted life-year from the Taiwan health care sector perspective and may be considered in future standard wound care.

Keywords: cost; care sector; care; health care; sector perspective

Journal Title: JAMA Network Open
Year Published: 2023

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